In a collaborative effort by McGill, Heidelberg, and Koç Universities and after harmonizing data from the three largest transplant registries worldwide, namely CTS, SRTR, and ANZDATA, the impact on organ transplant outcomes of sex was investigated in more than 400,000 kidney transplant recipients. In a series of articles listed below, important insights were provided on the intricate interplay between recipient and donor sex and age-dependent graft and patient survival in kidney transplantation.

  1. Vinson AJ, Zhang X, Dahhou M, Süsal C, Döhler B, Sapir-Pichhadze R, Cardinal H, Melk A, Wong G, Francis A, Pilmore H, Foster BJ. Age-dependent Sex Differences in Graft Loss After Kidney Transplantation. Transplantation. 2022 Jul 1;106(7):1473-1484. doi: 10.1097/TP.0000000000004026.
  2. Vinson AJ, Zhang X, Dahhou M, Süsal C, Döhler B, Melk A, Sapir-Pichhadze R, Cardinal H, Wong G, Francis A, Pilmore H, Foster BJ. A multinational cohort study uncovered sex differences in excess mortality after kidney transplant. Kidney Int. 2023 Jun;103(6):1131-1143. doi: 10.1016/j.kint.2023.01.022.
  3. Melk A, Sugianto RI, Zhang X, Dahhou M, Döhler B, Süsal C, Sapir-Pichhadze R, Wong G, Foster BJ. Influence of donor sex and age on graft outcome in kidney transplantation. Nephrol Dial Transplant. 2023 Aug 18:gfad181. doi: 10.1093/ndt/gfad181.
  4. Vinson AJ, Zhang X, Dahhou M, Süsal C, Döhler B, Sapir-Pichhadze R, Cardinal H, Melk A, Wong G, Francis A, Pilmore H, Foster BJ. A Multinational Cohort Study Examining Sex Differences in Excess Risk of Death With Graft Function After Kidney Transplant. Transplantation. 2024 Jan 26. doi: 10.1097/TP.0000000000004915.